ncRNA name | Malat1 |
ncRNA Category | lncRNA |
ID | 72289 |
Ensembl | ENSMUSG00000092341 |
Synonyms | Neat2; AI647968; 2210401K01Rik; 9430072K23Rik |
Disease name | diabetic retinopathy (DR) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | microarray, qPCR |
Expression pattern | up-regulated |
Functional description | Approximately 303 lncRNAs were aberrantly expressed in the retinas of early DR, including 214 downregulated lncRNAs and 89 upregulated lncRNAs. In addition, MALAT1 was significantly upregulated in an RF/6A cell model of hyperglycemia, in the aqueous humor samples, and in fibrovascular membranes of diabetic patients. |
PubMed ID | 24436191 |
Year | 2014 |
Title | Aberrant expression of long noncoding RNAs in early diabetic retinopathy. |
Drug-related ncRNA | NO |
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